Use of dexamethasone and prednisone in acute asthma exacerbations in pediatric patients.
نویسندگان
چکیده
QUESTION Children frequently present to my rural emergency department with asthma exacerbations. Should I prescribe systemic corticosteroids? If so, which systemic corticosteroid should I prescribe? ANSWER A short course of steroids is indicated in the treatment of asthma exacerbations. Both prednisone (1 to 2 mg/kg daily for 5 days) and dexamethasone (0.3 to 0.6 mg/kg daily for 1 to 5 days) are effective in reducing hospital admissions and unscheduled return to care, with minimal side effects.
منابع مشابه
Is dexamethasone an effective alternative to oral prednisone in the treatment of pediatric asthma exacerbations?
BACKGROUND A short course of systemic corticosteroids is an important therapy in the treatment of pediatric asthma exacerbations. Although a 5-day course of oral prednisone or prednisolone has become the most commonly used regimen, dexamethasone has also been used for a shorter duration (1-2 days) with potential for improvement in compliance and palatability. We reviewed the literature to deter...
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Introduction: Prednisolone is a key component in the treatment of severe asthma. Recent studies show that dexamethasone is a promising option due to its easier dosage regimen and better tolerance. However, little is known about the efficacy of dexamethasone in patients. The aim of this study was to compare the effects of dexamethasone and prednisolone on the control of asthma attacks. Methods...
متن کاملA cost-effectiveness analysis of dexamethasone versus prednisone in pediatric acute asthma exacerbations.
OBJECTIVES The objective was to evaluate the cost-effectiveness of dexamethasone versus prednisone for the treatment of pediatric asthma exacerbations in the emergency department (ED). METHODS This was a cost-effectiveness analysis using a decision analysis model to compare two oral steroid options for pediatric asthma patients: 5 days of oral prednisone and 2 days of oral dexamethasone (with...
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BACKGROUND AND OBJECTIVE Dexamethasone has been proposed as an equivalent therapy to prednisone/prednisolone for acute asthma exacerbations in pediatric patients. Although multiple small trials exist, clear consensus data are lacking. This systematic review and meta-analysis aimed to determine whether intramuscular or oral dexamethasone is equivalent or superior to a 5-day course of oral predni...
متن کاملDexamethasone for Acute Asthma Exacerbations in Children: A Meta-analysis abstract
BACKGROUND AND OBJECTIVE: Dexamethasone has been proposed as an equivalent therapy to prednisone/prednisolone for acute asthma exacerbations in pediatric patients. Although multiple small trials exist, clear consensus data are lacking. This systematic review and meta-analysis aimed to determine whether intramuscular or oral dexamethasone is equivalent or superior to a 5-day course of oral predn...
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ورودعنوان ژورنال:
- Canadian family physician Medecin de famille canadien
دوره 55 7 شماره
صفحات -
تاریخ انتشار 2009